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The Rainbow Reader Vol. 1 (Aa-Mm): A Research Based Intervention Program

Building and Environment, 45 4. International Journal of Ventilation, 8 2. What are the innovation challenges? Fast Track to Success: Supporting Service Innovation through Knowledge Management. Fifth International Conference on Construction in the 21st Century: Architectural Engineering and Design Management, 5 4. International Journal of Care Pathways, 13 1. Institute for Sustainability Conference, Feb , London. Shelter Cymru Conference, June 25 , Swansea. Institutional Investors and Climate Change.

Wiley finance series Journal of Property Research, 26 1. A manpower planning perspective. Qualitative data analysis for construction research: International Journal of Ventilation, 8 1. The British Institute of Facilities Managers. Science for Environment Policy: The University of West England, Bristol.

Intelligence in Assisted Homes, Bruges, Belgium. Design aspiration and operational shortcoming. Building our health system around people and their needs, Gold Coast, Australia. Design sentiments and the knowledge chasm. Architectural Engineering and Design Management, 5 Special is. Implementing a sustainability policy. Journal of Building Research and Information, 37 2. The role of visual representations as 'epistemic objects'. Organization Studies, 30 1. Advancing Effective Virtual Organisations.

The case of Heathrow's Terminal 5 project. Use of science and technology in business: Exploring the impact of using activity for systems, organizations and people. Emerald, Bingley UK, pp. Construction facing worldwide challenges, Dubrovnik, Croatia. Complying with the code for sustainable homes: Philosophical Transacions of the Royal Society A: Mathmatical, Physical and Engineering Sciences, Construction Management and Economics, 27 The story of construction management.

Current status, future prospects and challenges. International workshop on the socio-economics of ageing, Lisbon, Portugal. Include , Royal College of Art. Social shaping in action. Engineering, Construction and Architectural Management, 16 6. Construction Management and Economics, 27 6. Construction Management and Economics, 27 3.

Journal of Facilities Management, 7 2. Building and Environment, 44 9. Journal of Information and Knowledge Management, 8 3. Journal of Knowledge Management, 13 3. The case of a light emitting diode module start-up company. Wiley Blackwell, Oxford,UK, pp Intelligent Buildings International Journal, 1 1. Intelligent Buildings International Journal, 1 2. Journal of Centre South University, 16 Supplement. Information systems in the changing era: International Journal of Law in the Built Environment, 1 3. Information, Process, Management, 9 4. Engineering, Construction and Architectural Management, 16 2.

Construction Management and Economics, 27 7. Construction Management and Economics, 27 5. This is an Impact Assessment question. Mercato Concorrenza Regole, 10 2. Material Culture and Technology in Everyday Life: Intersections in Communications and Culture Peter Lang, New York, pp. Embedding sustainable facilities management in your organization, Keble College, Oxford. Innovation and Research Focus Renewable Energy, 34 9 Special.

Building and Environment, 44 Renewable Energy, 34 W65, W55 and W86, Dubrovnik, Croatia. Findings in Built and Rural Environments. Energy and Buildings, 40 Energy and Buildings, 40 7. Indoor Air , Copenhagen, Denmark. Redefining healthcare infrastructure, integrating services, technologies and the built environment, Imperial College, London. Conference on Efficient Buildings, Faro, Portugal, pp. Learning in a virtual environment. Trust and New Technologies: Marketing and Management on the Internet and Mobile Media.

Edward Elgar Publishing, Cheltenham, pp. EuroMed Journal of Business, 3 3. Wiley- Blackwell, Oxford, UK, pp The cases of the buildings schools for the future programme. Journal of Urban Regeneration and Renewal , 2 2. Applied Catalysis B-Environmental, 78 Building and Environment, 43 6. Building and Environment, 43 3. Potential applications to intelligent buildings. Dalian Univ Technol Press, Dalian, pp. Light reflectance value LRV of a surface - Method of test.

British Standards Institution, London. Housing for People with Sight Loss: A Thomas Pocklington Design Guide. Luce E Design, Balkan Light , Ljubljana, Slovenia, pp. International Journal of Information Quality, 2 2.

An explanatory framework and research agenda. A tool for post-project risk assessment. Automation in Construction, 18 1. Urban Studies, 45 1. A global survey of RICS members and their engagement with the sustainability agenda. Journal of Property Investment and Finance, 26 6.

Transformation through Construction, Dubai. Architectural Engineering and Design Management, 4 Solar Energy, 82 4. Advanced Corporate Learning, 1 1. The costs of substituting and supplementing care with assistive technology. British Journal of Occupational Therapy, 71 4. Plant Journal, 56 4. A case study of Stanhope plc. Corporate Social Responsibility in the Construction Industry. The case for middle-range theories. Building Research and Information, 36 6.

Building Research and Information, 36 5. Construction Management and Economics, 26 1. Issues, approaches and implication. Developing and implementing data management practices in construction work. Contexts, relative boundedness and actor-network theory. Construction Management and Economics, 26 A case study of English law. Advantages, disadvantages, and its implementation into English and Dutch law. Construction Supply Chain Management Handbook.

Advanced Research Methods in the Built Environment. Journal of the Human-Environmental System, 11 2. From being to becoming. Journal of Construction Procurement, 14 1. Construction Management and Economics, 26 9. Stakeholder management and organizational wealth: Preston and Sybille Sachs. Construction Management and Economics, 26 6. Stakeholder theory and organizational ethics.

Association of Researchers in Construction Management, Vol. Acta Energiae Solaris Sinica, 5. Interaction of airflow structures and ventilation efficiency. Construction Information Quarterly, 10 1. Energy Policy, 36 1. Energy Conversion and Management, 49 2.

Access by Design International Journal of General Systems, 37 2. Information and knowledge management: Information and knowledge management - helping the practitioner in planning and building. Lesson learnt from the construction industry. Florence School of Regulation, Florence. University of British Columbia Press, pp. International Regulatory Reform Report International Regulatory Reform Monitor Environment and Planning A, 40 Qualitative Inquiry, 14 7. Journal of Cereal Science, 48 1.

Designing for services - Multidisciplinary perspectives. Coordinating design work across a large construction project. Academy of Management, Anaheim, CA. Long Range Planning, 41 1. Evolution of Business Knowledge. Time and turbulence in digital technologies and practices. Chongqing University Press in Chinese.

International Journal of Information Management, 28 4. Empirical investigation in engineering. Building and Environment, 42 1. Building and Environment, 42 4. Energy Conversion and Management, 48 3.

1. Introduction

Governing Threats in the New Millennium. Engineering Failure Analysis, 14 5. Identifying suitable procurement and briefing processes. Clima WellBeing Indoors, Helsinki. Energy and Buildings, 39 4. Building and Environment, 42 5. The Value Manager, 13 2. University of Reading, pp People and Culture in Construction: Urban Studies, 44 Proceedings of the Royal Society A, International Journal of Low Carbon Technologies, 2 4.

International Networking for Young Scientists: Construction Management and Economics: Aesthetic knowledge and knowing in design. Organization Studies, 28 5. Building Research and Information, 35 1 Special. Nordic Conference in construction economics and organisation, University of Technology, Lulea, p. Innovations in structural engineering and construction, Melbourne, Australia, pp. Construction Management and Economics, 25 9. How adaptable are existing properties? British Journal of Occupational Therapy, 70 1. Construction for Development, Cape Town, pp. Construction Management and Economics, 25 Architectural Engineering and Design Management, 3 1.

Construction Management and Economics, 25 6. Construction Management and Economics , 25 7. Transforming practices and technologies in construction work. The role of technology in the production of construction practice. Managing the construction of buildings, Copenhagen Business School. Balancing rigour and relevance. A critical review of construction future studies. Construction Management and Economics, 25 5. Composite Structures, 78 3. Should we pay for performance? Physical modelling and anatomical evaluation of an unusual feeding method. PLoS Biology, 5 8.

A temporal bone study. Building and Environment, 42 2. Engineering, Construction and Architectural Management, 14 1. Relationships in developing new procurement. Practitioners, practices, and practice. Choosing of an appropriate research methodology. Information, Process, Management, 7 3. Journal of Chongqing University. Energy and Buildings, 39 Journal of Central South University of Technology, An improved SWOT approach.

Design Studies, 28 3. Building Research and Information, 35 Special Is. Shaping the future - the next five years, Keble College, Oxford. Building and Environment, 42 6. Challenge of the Industry for the New Millennium, Pts 1 and 2. I O S Press, Amsterdam, pp. Packaging Technology and Science, 20 1. Construction Management and Economics, 25 7. International Journal of Project Management, 25 8. Construction Management and Economics, 25 2. Journal of Materials Science, 42 Journal of Construction Management and Engineering, 5. Building Research and Information, 35 4 Special.

Worldviews, Science and Us: World Scientific, New York, pp. ISBN ebook. The 7th biennial conference on Environmental Psychology, Bayreuth, Germany. Method of investigation of a commercial building's comfort levels. Highlighting energy efficiency concerns. Journal of Risk Research, 10 2. Design Issues, 23 2. Managing the Construction of Buildings, Copenhagen, Denmark. Mowery and Richard R. Organization Studies, 28 4.

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Dances of Individuals and Organization, Vienna, Austria. European Journal of Operational Research, 3. Clima Wellbeing Indoors, Helsinki. The Design Society, pp. ISBN Full paper number: Applied Energy, 83 4. British Journal of Management, 17 4. A twenty year view. Journal of Bionic Engineering, 3 1. Journal of Facilities Management, 4 3.

Journal of Construction Management and Engineering, 3. Spon Press, London and New York, pp Energy and Buildings, 38 5. Eastham, and Leonhard E. Journal of Construction Management and Engineering, 9. The Construction Information Quarterly, 8 1. Automation in Construction, 15 6. Journal of Management Development, 25 1. Hong Kong Polytechnic Univ, Kowloon, pp.


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Asia Academy of Management 5th Conference, Tokyo. Journal of Property Research, 23 3. Drivers, barriers and critical success factors. Property Management, 24 5. Journal of Property Investment and Finance, 24 6. Energy and Buildings, 38 8. International Journal of Ventilation, 4 4. Modelling, assessment and control of indoor air quality for FM professionals. Material consequences and localised resistance. Building Research and Information, 34 2. The Management of Projects: Wiley-Blackwell, Oxford, Context, discourse and self-identity. Theory, practice and opinions.

Construction in the XXI Century: Local and global challenges, Rome, Italy. Journal of Construction in Developing Countries, 11 1. Journal of Harbin Institute of Technology. Comercial management of projects: The impact of on-line manuscript management on the management of a peer-reviewed journal.

Taylor and Francis, pp Engineering, Construction and Architectural Management, 13 5. A dynamic capabilities perspective. Carbon Capture and its Storage. International Journal of Construction Management, 6 1. British Journal of Occupational Technology, 69 3. New horizons for ageing research. Quality in Ageing and Older Adults, 7 1. Benefits to and acceptance by older people.

CME Geriatric Medicine, 8 2. Polarized perspectives and the search for the middle ground. Local and global challenges, Rome, executive paper on CD Rom. W92 Conference on Procurement Systems, Salford, pp. Is there a case for integrated solutions in construction? Construction Management and Economics, 24 3. Acta Energiae Solaris Sinica. Journal of Supply Chain Science and Technology 8. Commercial management of projects: A checklist for the action researcher.

W65 and W55, Oct , Rome, Italy. Construction Management and Economics, 24 University of Salford, Manchester. The spoken representation of form and functional meaning. Design Studies, 27 2. Computer supported cooperative work in design II. Springer, Berlin Heidelberg, pp. Trees-Structure and Function, 20 5. Implications for the construction industries in developing countries. Procs W Construction in developing countries: Journal of Fish Biology, 68 2. Construction in Developing Economies: An empirical examination of the role of institutional norms. Construction Management and Economics, 24 6.

Journal of Building Appraisal, 2 2. Journal of Materials Science, 41 4. Building Research and Information, 34 1. International Journal of Project Management, 25 2. An application and extension of the Bon Qualitative Input-Output model. Construction Management and Economics, 24 7 Special. Actor-network theory and strategic organization. Strategic Organization, 4 3. The implementation of green design and green building schemes. Journal of Construction Management and Engineering, Construction Management and Economics, 24 4.

Construction Information Quarterly, 8 4. How to integrate productivity in life cycle cost analysis of buildings services. Federation of European Heating and Airconditioning Associations, pp. JIT implementation status in the ready-mixed concrete industry. An analytical comparison of inventory costs in the ready mixed-concrete industry. International Journal of Production Economics, 1. Materials Science Forum, Journal of Construction Management and Engineering, 6. Engineering, Construction and Architectural Management, 13 2.

Sustainable Built Environment and Construction. Chongqing University, Chongqing, pp. Introduction to Sustainable Urban and Architectural Design. China Architectur and Building Press, China, pp. Information, Process, Management, 6 1. A new way of determining ductile fracture toughness and strength. Engineering Fracture Mechanics, 72 6. International Journal of Mechanical Science, 47 Applied Ergonomics, 36 2. Journal of Experimental Biology, Biological Sciences Review, 17 4.

Materials World, 13 4. Automation in Construction, 14 3. International Journal of Offshore and Polar Engineering, 15 3. Journal of Engineering for the Maritime Environment , 4. Ieee Computer Soc, Los Alamitos, pp. Hoist and Haul, Perth. Challenges, solutions and torsion. Assessment case study session. ISO and the construction industry: Journal of Management in Engineering, 21 3. Construction Innovation, 5 1. Computer-Aided Civil and Infrastructure Engineering. A decision-making model for sustainable partnerships in construction.

Construction Sustainability and Innovation, Hong Kong. Tsinghua University Press, Beijing, pp. Chartered Institution of Building Services Engineers. Managing inclusive design guide. Managing inclusive design Guide. Include , Royal College of Art, London. Journal of Biomechanical Engineering, 2. The Impact of Information and Communications Technology. Journal of Property Investment and Finance, 23 6. Property Management, 23 2. The case of managed and conventional offices. Journal of Property Investment and Finance, 23 5. Local Economy, 23 6. International Journal of Project Management, 23 7.

Harnessing the role of FM in the design processes through post-occupancy evaluation studies. Combining forces - Advancing facilities management and construction through innovation, 13 - 16 Jun , Helsinki, Finland, pp. A framework explaining construction industry competitiveness. Blackwell Publishing, Oxford, pp Making Buildings Accessible Special Report, Workplace Law Network, pp.

Building and Environment, 40 3. Value Magazine, 14 3. Arenas of enactment, models of diffusion and the meaning of 'leanness'. Building Research and Information, 33 6. Construction Management and Economics, 23 6. Report on a seminar held at the University of Reading, 26th November Construction Labour Review, 4.

Peter Reed, "Railtracks in the Sky: Journal of Air Transport Management, 11 4. The national construction college site management course. The case of the CITB site management course. A comparison of government and commercially available data Journal of Financial Management of Property and Construction, 10 2. Shifts in codes of conduct. Journal of Strain Analysis for Engineering Design, 40 7.

Journal of Strain Analysis for Engineering Design, 40 6. Applied Mechanics and Materials, International Journal of Construction Management, 5 1. Using systems theory, technological forecasting and scenario planning. Engineering, Construction and Architectural Management, 12 4. Proceedings of Institution of Civil Engineering. Construction Management and Economics, 23 2. House of Lords Science and Technology Committee.

Include, Royal College of Art, London. Building and Environment, 40 7. Relating innovation diffusion concepts to the stage of the diffusion process. Construction Management and Economics, 23 8. The introduction of an awareness threshold level concept. Construction Management and Economics, 23 1. Clima, October , Lausanne, Switzerland. Journal of Financial Management of Property and Construction, 10 1. Indoor Air , Beijing, China. Taylor and Francis, pp. Architectural Journal, 52 2. Construction procurement - the impact of cultural differences and systems on construction performance, Feb , Las Vegas, USA, pp.

International Journal of Antimicrobial Agents, 26 1. Improving access for disabled people. QUT Research week , Brisbane. Journal of Materials Science, 40 Building Research and Information, 33 2.

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Journal of Telemedicine and Telecare, 11 Supplement. Engineering, Construction and Architectural Management, 12 5. Beijing Inst Technology Pr, Beijing, pp. International Journal of Energy and Building, 37 6. Renewable Energy, 30 Building for the future, Toronto. Journal of Materials Science, 39 8. Engineering fracture mechanics, 12 2. Biological Reviews, 79 2. Air and surface temperature measurements.

Renewable Energy, 29 2. The all-cause mortality risk for low-fit or sedentary diabetics is more than 2 times higher compared with physically fit men and women diabetics regardless of body weight [ 95 — 97 ]. Low physical activity levels and poorer fitness status are inexorably associated with aging and age-related unfavorable changes in several physiological and metabolic processes, including declines in muscle mass, strength, endurance, and aerobic fitness, with reciprocal increases in adiposity, insulin resistance, metabolic syndrome, and type 2 diabetes mellitus [ 29 , 98 ].

Individuals with diabetes mellitus, in addition, show an accelerated decline in oxidative capacity maximum oxygen uptake , muscle mass, muscle strength, and glycemic control with aging [ 99 — ]. Reduced exercise capacity is a strong predictor of all-cause mortality in older individuals with and without diabetes mellitus [ 49 ]. Since aging and reduced exercise capacity often coexist, and increased fitness is inversely related to mortality risk, we assessed the relationship between aging and exercise capacity in older individuals with diabetes mellitus.

Our findings show that greater exercise capacity or fitness is associated with lower mortality risk in individuals aged 50 to 65 years old as well as those older than 65 with type 2 diabetes mellitus. Because poorer fitness and lower physical activity levels are strongly associated with aging and age-related unfavorable changes in several physiological and metabolic processes, it is imperative that healthcare providers encourage a physically active lifestyle regardless of age.

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Because African-Americans have a 2- to 6-fold higher risk for developing diabetes mellitus [ ] and approximately double the diabetes mellitus death rate [ ] we probed for racial differences on the impact of exercise capacity on mortality risk in the Veterans Exercise Testing Study [ ]. We found that exercise capacity was a strong predictor of mortality in black and white men with type 2 diabetes mellitus.

Recent evidence form large epidemiologic studies support significantly higher mortality risk only in individuals with relatively low body mass index BMI with no excess risk associated with overweight or obese individuals. This puzzling observation, termed obesity paradox [ 56 , ], has not been investigated in the context of fitness status in diabetic individuals.

We therefore, assessed the interrelationship between exercise capacity, BMI and mortality risk, in middle-aged and older African-American and Caucasian veterans with type 2 diabetes mellitus [ , ]. The lower mortality risk associated with increased fitness may be modulated by the exercise-related favorable effects on carbohydrate and fat metabolism. It is known that exercise is an insulin-independent stimulant of glucose uptake by the working muscle cells via the GLUT-4 transporter [ ].

Exercise-induced translocation of GLUT-4 transporters is modulated by several factors related to muscular contractions such as increased calcium concentrations [ ], hypoxia [ ] and nitric oxide [ ]. Exercise training studies support that both aerobic and anaerobic exercise training regimens improve glucose uptake and insulin sensitivity [ , ]. The recent discovery of the hormone Irisin provide a mechanistic explanation for the protection exercise offers against metabolic diseases and perhaps a network of other chronic human diseases [ 23 ].

Moreover, mice engineered to express high irisin levels in blood were resistant to obesity and diabetes [ 23 ]. The most consistent findings from epidemiologic studies and randomized controlled trials supports that aerobic exercise of adequate intensity, duration, and volume results in favorable and independent alterations in high-density lipoprotein HDL cholesterol, with less consistency for reductions in total cholesterol, triglycerides, and low-density lipoprotein cholesterol concentrations for both normolipidemic and dyslipidemic individuals [ — ].

Exercise training can also attenuate the reductions in HDL cholesterol [ , ] usually observed with low-fat diets [ , ]. Overall, no consistent evidence is available to indicate that HDL cholesterol changes related to exercise are associated with age, ethnicity, or gender [ ]. However, greater HDL cholesterol changes in men versus women, particularly when exercise is combined with a prudent diet, have been reported by some [ , ], but disputed by others [ , ].

Some studies suggested that exercise training does not appear to improve HDL cholesterol concentrations beyond the improvements seen with hormone replacement therapy [ ], whereas others have shown synergistic effects between hormone replacement therapy and exercise training [ ]. Epidemiological and interventional study evidence support that the magnitude of the changes in HDL cholesterol is related more to the volume of exercise than the intensity [ — ]. A dose-response relationship between the volume of exercise and HDL cholesterol changes has also been suggested by this study.

For each mile increase in weekly distance, HDL cholesterol concentration increased 0. Similar findings were reported by others [ — ]. In women, menopausal status does not appear to influence this dose-response relationship [ ]. This theory states that atherosclerosis develops as a result of repetitive injury and ongoing inflammatory process of the arterial endothelium, initiated by a pathogen. A number of blood markers have been identified that are associated with inflammation, most notably white blood cell count, C-reactive protein CRP , homocysteine, fibrinogen, and other proteins involved in the immune response.

The most widely studied inflammatory blood marker is CRP [ ]. Several studies have shown that elevated levels of CRP are directly associated traditional cardiac risk factors and independently increase the risk of cardiovascular disease and mortality in both healthy individuals and patients with existing cardiovascular disease [ — ]. Acute exercise induces a transient inflammatory response, including heightened CRP concentration.

This is most likely due to joint and muscle inflammation after vigorous activity. However, regular, sustained exercise has been shown to suppress inflammation. The findings of epidemiological studies consistently support of an inverse association between CRP, other inflammatory markers, and fitness. Collectively, these [ — ] and other findings [ 10 ] support that the health benefits including lower mortality risk associated with increased fitness may be explained in part by the inverse association between fitness and inflammatory markers.

The potential for death is inherent in structured exercise programs or physical exertion. The first death mentioned as a result of physical exertion is recorded by the Greeks. Legend has it that Phidippides ran from the battlefield of Marathon to Athens approximately 26 miles away to carry the news to the Athenians that they were victorious against the invading Persians.

He reached Athens in perhaps 3 hours, delivered his message, and died shortly thereafter from exhaustion. Was it the mile run that killed Phidippides? Less known is the fact that, only days prior to the battle at Marathon, Phidippides was sent to Sparta to ask for help. He ran the rugged, mountainous mile course in about 36 hours to deliver the message. Afterwards, Phidippides ran that same mile trail back to Athens with the disappointing news that the Spartans refused to send warriors to help the Athenians.

A few days later he was in the battle of Marathon where, in all likelihood, Phidippides had been carrying messages back and forth to the different generals on the field during the day's battle. It was at the end of that last day when he was charged with running to Athens to deliver the victorious news [ 29 ]. Although we will never know exactly what killed Phidippides, the numerous modern marathon and ultramarathon races run by millions of runners annually are proof that humans are capable of such a task when trained properly.

On the other hand, the occasional death of a runner reminds us of our vulnerabilities. Almost all exercise-related deaths in previously asymptomatic adults without prior history of coronary heart disease have been the result of atherosclerotic plaque rupture in one of the coronary arteries that led to an acute coronary thrombosis [ — ].

Recent findings also suggest that demand ischemia i. Because the most common cause of cardiac complications is atherosclerotic coronary artery disease, the risk of exercise varies according to the population. In older populations where the prevalence of coronary atherosclerotic disease is high, the risk of death during exercise or physical exertion will be correspondingly high [ ].

Interestingly, cardiac arrest, most commonly attributable to hypertrophic cardiomyopathy or atherosclerotic coronary disease, occurs primarily among male marathoners [ ]. Several studies have also shown an inverse association between the risk of an event and the fitness status of the individual [ — ]. The risk of a cardiac event during physical exertion for sedentary individuals is reported to be approximately 2.

Despite this risk, the exercise-related cardiac event is relatively rare even in high-risk populations. The incidence of exercise-related deaths is the Rhode Island study [ ] over a five-year period was 1 death per year for every 15, male joggers with no know coronary heart disease and 1 death per year for every 7, in those with known coronary heart disease.

In general, the rate of sudden cardiac death and other cardiac events during exercise is estimated to be between 0 and 2 per , hours of exercise in the general population and 0. More recent evidence from a large cohort on marathon and half marathon runners concur with these findings. The incidence rates of cardiac arrest and sudden death during long-distance running races were 1 per , and 1 per , participants, respectively. This translates roughly into 0. In conclusion, it is clear that physical exertion is associated with a transient increase in risk for cardiac events.

This risk is significantly higher for older and sedentary individuals engaging in an exercise program. Therefore, it is prudent that such individuals consult their physician to evaluate the presence of subclinical coronary artery disease prior to engaging in an exercise program. The plethora of information and at time misinformation regarding exercise, fitness, and health within the last few decades is stunning and overwhelming for most individuals.

To minimize confusion for the patients, reduce the risk of injury, and to maintain exercise efficacy, health care providers must view exercise as an intervention similar to prescribing medication. The mode of exercise, its frequency, intensity and duration should be considered carefully. Moreover, exercise should be tailored to meet an individual's needs and abilities. This is especially true for special populations such as elderly, overweight or obese, hypertensive, and diabetic individuals. The current recommendations from the American Heart Association and the American College of Sports Medicine for middle-aged adults and older individuals [ 83 , 84 ] stated below should be followed.

National Center for Biotechnology Information , U. Published online Oct Author information Article notes Copyright and License information Disclaimer. Received Aug 5; Accepted Sep 7. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This article has been cited by other articles in PMC. Abstract A plethora of epidemiologic evidence from large studies supports unequivocally an inverse, independent, and graded association between volume of physical activity, health, and cardiovascular and overall mortality.

Introduction Over 2, year ago, Hippocrates noted the potential health benefits of daily exercise of moderate intensity such as a simple walk. Physical Activity and Mortality in Women The findings of recent large cohort studies in women, including the Women's Health Study, the Lipid Research Clinics Research Prevalence Study, and the Women Take Heart Project also support an inverse and graded association between increased physical activity and mortality in women [ 7 , 8 , 13 — 15 ]. Fitness Assessment Studies More recent studies assessed fitness status by standardized exercise protocols.

Association of Mortality Risk with Exercise Type, Duration, and Intensity Evidence from several studies suggests an independent contribution of the exercise mode and each exercise components intensity, duration, frequency to mortality risk [ 28 ]. Physical Activity and Cardiac Risk Factors 6.

Table 1 Classification of body weight and obesity based on BMI and waist circumference. Open in a separate window. Physical Activity, Fitness, Obesity, and Mortality Obesity and overweight are considered to be leading risk factors for a number of chronic health conditions, including diabetes mellitus, hypertension, coronary heart disease, and premature mortality.

Hypertension Chronic hypertension is a major and most common risk factor for developing cardiovascular disease and mortality [ 58 ]. Physical Activity, Fitness, and Hypertension The significant impact of increased physical activity or structured exercise programs on blood pressure control has been consistently documented by a number of well-controlled studies.

Exercise Blood Pressure Response Evidence supports that the blood pressure response to submaximal workloads is associated with left ventricular hypertrophy LVH. Physical Activity, Fitness, and Mortality Risk in Individuals with Hypertension A number of large and well-controlled epidemiologic studies have reported an inverse and graded association between exercise capacity and mortality risk in hypertensive individuals [ 9 , 27 , 88 ]. Diabetes Mellitus Evidence from large cohort studies supports that physical activity in general provides a highly effective way to delay or avert the development of diabetes mellitus in both men and women.

Physical Activity, Fitness, and Mortality Risk in Individuals with Type 2 Diabetes Mellitus Epidemiologic findings also support that increased physical activity is associated with lower mortality risk in individuals with type 2 diabetes mellitus. Physical Activity, Fitness, and Lipids The most consistent findings from epidemiologic studies and randomized controlled trials supports that aerobic exercise of adequate intensity, duration, and volume results in favorable and independent alterations in high-density lipoprotein HDL cholesterol, with less consistency for reductions in total cholesterol, triglycerides, and low-density lipoprotein cholesterol concentrations for both normolipidemic and dyslipidemic individuals [ — ].

Risk of Death during Physical Activity The potential for death is inherent in structured exercise programs or physical exertion. Exercise Recommendations for Health Benefits The plethora of information and at time misinformation regarding exercise, fitness, and health within the last few decades is stunning and overwhelming for most individuals.

Exercise should be primarily aerobic, supplemented by muscle-strengthening activities. The exercise intensity should be moderate brisk walking at 15 to 20 minutes per mile for most individuals and at even lower intensities for those unable to sustain such walking speeds. Moderate- and vigorous-intensity jogging activities can be combined for younger individuals or those able to sustain such intensities.

A gradual increase in the minimum exercise volume is recommended to maximize health benefits. In addition, a minimum of 2 days per week of light weight-resistance exercises involving the major muscle groups and designed to maintain or increase muscular strength and endurance is encouraged.

Coronary heart-disease and physical activity of work. Exercise capacity and mortality in black and white men. Kokkinos P, Myers J. Exercise and physical activity: Physical fitness and all-cause mortality: Influences of cardiorespiratory fitness and other precursors on cardiovascular disease and all-cause mortality in men and women. Changes in physical fitness and all-cause mortality: Walking compared with vigorous exercise for the prevention of cardiovascular events in women.

The New England Journal of Medicine. A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in women. Exercise capacity and mortality among men referred for exercise testing. Physical activity and reduced risk of cardiovascular events: Relationship of leisure-time physical activity and mortality: Fitness versus physical activity patterns in predicting mortality in men.

American Journal of Medicine. Ability of exercise testing to predict cardiovascular and all-cause death in asymptomatic women: Exercise capacity and the risk of death in women: James Women Take Heart Project. Relationship of changes in physical activity and mortality among older women. Usefulness of exercise testing in the prediction of coronary disease risk among asymptomatic persons as a function of the Framingham risk score. Results of a multicenter randomized clinical trial of exercise and long- term survival in myocardial infarction patients: Prognostic value of treadmill exercise testing in elderly persons.

Annals of Internal Medicine. The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. Physical activity as an index of heart attack risk in college alumni. American Journal of Epidemiology. Physical activity, all-cause mortality, and longevity of college alumni. Exercise type and intensity in relation to coronary heart disease in men. Physical activity and the incidence of coronary heart disease. Annual Review of Public Health. Physical activity levels and coronary heart disease.

Analysis of epidemiologic and supporting studies. Medical Clinics of North America. Punsar S, Karvonen MJ. Physical activity and coronary heart disease in populations from East and West Finland. Exercise capacity and mortality in hypertensive men with and without additional risk factors. Physical activity and all-cause mortality: Medicine and Science in Sports and Exercise. Physical Activity and Cardiovascular Disease Prevention.

Jones and Bartlett; Exercise capacity and mortality in older men: Two weeks of high-intensity aerobic interval training increases the capacity for fat oxidation during exercise in women. Journal of Applied Physiology. Effects of high-intensity interval walking training on physical fitness and blood pressure in middle-aged and older people. Aerobic interval training vs. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: Perk J, Mathes P, editors. Physical activity and public health: Exercise in the prevention of coronary heart disease: Preventing and Managing the Global Epidemic.

American Heart Association call to action: Body weight and mortality: Body weight and mortality among women. The effect of age on the association between body-mass index and mortality. Caloric imbalance and public health policy. The human obesity gene map: Clinical Guidelines on the identification, evaluation and treatment of ovetweight and obesity in adults. Lung and Blood Institute, Relationship of leisure-time physical activity and occupational activity to the prevalence of obesity. International Journal of Obesity. Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men.

Cardiorespiratory fitness and adiposity as mortality predictors in older adults. Adiposity as compared with physical activity in predicting mortality among women. Obesity as compared with physical activity in predicting risk of coronary heart disease in women. Physical activity, cardiorespiratory fitness, and adiposity: Physical inactivity, excess adiposity and premature mortality. Body mass index and mortality in heart failure: Obesity paradox and cardiorespiratory fitness in 12, male veterans aged 40 to 70 years. The obesity paradox and weight loss.

Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: Blood pressure, stroke, and coronary heart disease. Part 1, prolonged differences in blood pressure: World Health Report Reducing Risks, Promoting Healthy Life. World Health Organization; Does blood pressure inevitably rise with age?: Relationships of quality-of-life measures to long-term lifestyle and drug treatment in the treatment of mild hypertension study.

Archives of Internal Medicine. Exercise capacity and all-cause mortality in prehypertensive men. American Journal of Hypertension. Exercise characteristics and the blood pressure response to dynamic physical training. Effects of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors.

American College of Sports Medicine position stand. Exercise as hypertension therapy. Blood pressure lowering effect of low intensity aerobic training in elderly hypertensive patients. Influence of age and gender on exercise training-induced blood pressure reduction in systemic hypertension. American Journal of Cardiology. Effects of regular exercise on blood pressure and left ventricular hypertrophy in African-American men with severe hypertension. Effect of exercise training in to year-old persons with essential hypertension. Differential effects of exercise training intensity on blood pressure and cardiovascular responses to stress in borderline hypertensive humans.

Effect of aerobic exercise on blood pressure: Effects of endurance training on baroreflex sensitivity and blood pressure in borderline hypertension. Exercise training in mild hypertension: Exercise capacity and h blood pressure in prehypertensive men and women.

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